Laboratory of Biochemical Risk Analysis
نویسندگان
چکیده
We describe melphalan pharmacokinetics in 26 patients treated by isolated limb perfusion (ILP). Group A (n = 11) were treated with a bolus of melphalan (1.5 mg kg-'), and in a phase I study the dose was increased to 1.75 mg kg-'. The higher dose was given as a bolus to Group B (n = 9), and by divided dose to Group C (n = 6). Using high performance liquid chromatography (HPLC) the concentrations of melphalan in the arterial and
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ورودعنوان ژورنال:
- Environmental Health Perspectives
دوره 101 شماره
صفحات -
تاریخ انتشار 1993